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Multiscale modeling is becoming essential for accurate, rapid simulation in science and engineering. This book presents the results of three decades of research on multiscale modeling in process engineering from principles to application, and its generalization for different fields. This book considers the universality of meso-scale phenomena for the first time, and provides insight into the emerging discipline that unifies them, meso-science, as well as new perspectives for virtual process engineering.
Multiscale modeling is applied in areas including:
Jinghai Li is Vice-President of the Chinese Academy of Sciences (CAS), a professor at the Institute of Process Engineering, CAS, and leader of the EMMS (Energy-minimizing multiscale) Group.
Wei Ge, Wei Wang, Ning Yang and Junwu Wang are professors at the EMMS Group, part of the Institute of Process Engineering, CAS.
Xinhua Liu, Limin Wang, Xianfeng He and Xiaowei Wang are associate professors at the EMMS Group, part of the Institute of Process Engineering, CAS.
Mooson Kwauk is an emeritus director of the Institute of Process Engineering, CAS, and is an advisor to the EMMS Group.
The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens?
Written from the industry perspective and based on many years of experience, this book offers:
- Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs
- Guidance for exploration and modification of these programs to enhance the understanding of key principles
- Usage of differential equations to pharmacokinetic, pharmacodynamic and (patho-) physiologic problems thereby acknowledging their dynamic nature
- A range of topics from single exponential decay to adaptive dosing, from single subject exploration to clinical trial simulation, and from empirical to mechanistic disease modeling.
Students with an undergraduate mathematical background or equivalent education, interest in life sciences and skills in a high-level programming language such as MATLAB, are encouraged to engage in model-based pharmaceutical research and development.
The use of simulation modeling and analysis is becoming increasingly more popular as a technique for improving or investigating process performance. This book is a practical, easy-to-follow reference that offers up-to-date information and step-by-step procedures for conducting simulation studies. It provides sample simulation project support material, including checklists, data-collection forms, and sample simulation project reports and publications to facilitate practitioners' efforts in conducting simulation modeling and analysis projects.
Where Does the Special Needs Mom Go For Support? As a special needs mom we forget to take care of ourselves, because we are so busy. We are running like hamsters on a wheel, trying to find our way through this new world we live in. This level of busy is exhausting. When a friend asks you how are you doing, how do you respond? Do you tell them you're tired, frustrated, angry, or burnt out? Or, do you tell them about your child's latest challenge that's got you up against the wall? Have you forgotten to check in with yourself? To stop and take a break or catch your breath? You may be so exhausted you can't figure out how to take a break, you think you are out of options. The truth is you do have options. You have many options, all within the Becoming A Seriously Happy Special Needs Mom. The guide to finding your happy place that you won't find anywhere else. Practical tips, life lessons, and strategies to open your mind to new ways of thinking. Change the way you look at life and life will look different. Discover how you can create your Happy Place in a world that you never imagined for yourself. Find out how laughter will change your perspective and your attitude. Become the empowered and confident mother, wife, and friend in difficult situations. Relationships will blossom and your self confidence will soar. If you're looking for support for special needs moms, you're in the right place. Scroll to the top of the page and get started when you buy this book.
El que sabe que sabe es un sabio. S' ?guelo. El que no sabe que sabe esta dormido. Despi' ertalo. El que sabe que no sabe es sencillo. Instruyelo. ' El que no sabe que no sabe es un necio. Ap' artate de ' el (He who knows and knows he knows, he is wise. Follow him. He who knows and knows not he knows, he is asleep. Wake him. He who knows not and knows he knows not, he is simple. Teach him. He who knows not and knows not he knows not, he is a fool. Shun him.) Proverbio Arabe. Corrige al sabio y lo har' as m' as sabio, corrige al necio y lo har' as tu enemigo. Sedulo curavi, humanas actiones non ridere, non lugere, neque detestari, sed intelligere. (I have made a ceaseless e?ort not to ridicule, not to bewail, not to scorn human actions, but to understand them.) Benedictus de Spinoza (1632-1677).
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