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Development Of Innovative Drugs Via Modeling With Matlab

RRP $352.99

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The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens? Written from the industry perspective and based on many years of experience, this book offers: - Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs - Guidance for exploration and modification of these programs to enhance the understanding of key principles - Usage of differential equations to pharmacokinetic, pharmacodynamic and (patho-) physiologic problems thereby acknowledging their dynamic nature - A range of topics from single exponential decay to adaptive dosing, from single subject exploration to clinical trial simulation, and from empirical to mechanistic disease modeling. Students with an undergraduate mathematical background or equivalent education, interest in life sciences and skills in a high-level programming language such as MATLAB, are encouraged to engage in model-based pharmaceutical research and development.


A Model Of Prevention

RRP $402.99

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An autobiography of a ground-breaking medical doctor. Dr. David A. Hamburg started as a medical student with interest in stress disorders, paying special attention to the propensity toward violence, including the evolution of human aggression. This lead him on a path to becoming one of the most highly celebrated doctors in America - he was a member of President Clinton's Committee of Advisors on Science and Technology and was awarded the Presidential Medal of Freedom (the highest civilian award of the United States). Most recently, he chaired committees at the United Nations and European Union on the prevention of genocide. This book will be inspirational for emerging scientists today.


Development Of Innovative Drugs Via Modeling With Matlab

RRP $574.99

Click on the Google Preview image above to read some pages of this book!

The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens?

Written from the industry perspective and based on many years of experience, this book offers:

- Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs

- Guidance for exploration and modification of these programs to enhance the understanding of key principles

- Usage of differential equations to pharmacokinetic, pharmacodynamic and (patho-) physiologic problems thereby acknowledging their dynamic nature

- A range of topics from single exponential decay to adaptive dosing, from single subject exploration to clinical trial simulation, and from empirical to mechanistic disease modeling.

Students with an undergraduate mathematical background or equivalent education, interest in life sciences and skills in a high-level programming language such as MATLAB, are encouraged to engage in model-based pharmaceutical research and development.


Becoming Johanna

RRP $13.99

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Since the age of three, the austere conditions and strict directives of Peakie's Foundling Home have ruled 16-year-old Josefina Charo's life. Her inquisitive nature and love of books underscore an intelligence that allows her to graduate two years early from secondary school. However, she is crestfallen to learn Peakie's will not provide a higher education, nor will she be permitted to leave because she's too young. Her spirit dampened, she searches for a way to escape her prison and grabs her chance when she sees it, but she soon discovers the harsh realities of being on her own. Life is difficult, at best, for a teenage girl with no real world experience.


Analog Behavioral Modeling With The Verilog-a-language

RRP $546.99

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Analog Behavioral Modeling With The Verilog-A Language provides the IC designer with an introduction to the methodologies and uses of analog behavioral modeling with the Verilog-A language. In doing so, an overview of Verilog-A language constructs as well as applications using the language are presented. In addition, the book is accompanied by the Verilog-A Explorer IDE (Integrated Development Environment), a limited capability Verilog-A enhanced SPICE simulator for further learning and experimentation with the Verilog-A language. This book assumes a basic level of understanding of the usage of SPICE-based analog simulation and the Verilog HDL language, although any programming language background and a little determination should suffice.
From the Foreword:
`Verilog-A is a new hardware design language (HDL) for analog circuit and systems design. Since the mid-eighties, Verilog HDL has been used extensively in the design and verification of digital systems. However, there have been no analogous high-level languages available for analog and mixed-signal circuits and systems.
Verilog-A provides a new dimension of design and simulation capability for analog electronic systems. Previously, analog simulation has been based upon the SPICE circuit simulator or some derivative of it. Digital simulation is primarily performed with a hardware description language such as Verilog, which is popular since it is easy to learn and use. Making Verilog more worthwhile is the fact that several tools exist in the industry that complement and extend Verilog's capabilities ...
Behavioral Modeling With the Verilog-A Language provides a good introduction and starting place for students and practicing engineers with interest in understanding this new level of simulation technology. This book contains numerous examples that enhance the text material and provide a helpful learning tool for the reader. The text and the simulation program included can be used for individual study or in a classroom environment ...'
Dr. Thomas A. DeMassa, Professor of Engineering, Arizona State University



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